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Generation of avian-derived anti-B7-H4 antibodies exerts a blockade effect on the immunosuppressive response
For highly conserved mammalian protein, chicken is a suitable immune host to generate antibodies. Monoclonal antibodies have been successfully targeted with immunity checkpoint proteins as a means of cancer treatment; this treatment enhances tumor-specific immunity responses through immunoregulation...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390317/ https://www.ncbi.nlm.nih.gov/pubmed/33716253 http://dx.doi.org/10.1538/expanim.20-0178 |