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Generation of avian-derived anti-B7-H4 antibodies exerts a blockade effect on the immunosuppressive response

For highly conserved mammalian protein, chicken is a suitable immune host to generate antibodies. Monoclonal antibodies have been successfully targeted with immunity checkpoint proteins as a means of cancer treatment; this treatment enhances tumor-specific immunity responses through immunoregulation...

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Detalles Bibliográficos
Autores principales:	Lin, Tsai-Yu, Tsai, Tsung-Hsun, Chen, Chih-Tien, Yang, Tz-Wen, Chang, Fu-Ling, Lo, Yan-Ni, Chung, Ting-Sheng, Cheng, Ming-Hui, Chen, Wang-Chuan, Tsai, Keng-Chang, Lee, Yu-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Association for Laboratory Animal Science 2021
Materias:	Original
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390317/ https://www.ncbi.nlm.nih.gov/pubmed/33716253 http://dx.doi.org/10.1538/expanim.20-0178

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