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Profiling CD8(+) T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants

Cellular immunity is important in determining the disease severity of COVID-19 patients. However, current understanding of SARS-CoV-2 epitopes mediating cellular immunity is limited. Here we apply T-Scan, a recently developed method, to identify CD8(+) T cell epitopes from COVID-19 patients of four...

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Detalles Bibliográficos
Autores principales: Zhang, Hang, Deng, Shasha, Ren, Liting, Zheng, Peiyi, Hu, Xiaowen, Jin, Tengchuan, Tan, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390359/
https://www.ncbi.nlm.nih.gov/pubmed/34506741
http://dx.doi.org/10.1016/j.celrep.2021.109708