Bottleneck size and selection level reproducibly impact evolution of antibiotic resistance

During antibiotic treatment, the evolution of bacterial pathogens is fundamentally affected by bottlenecks and varying selection levels imposed by the drugs. Bottlenecks—that is, reductions in bacterial population size—lead to an increased influence of random effects (genetic drift) during bacterial...

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Detalles Bibliográficos
Autores principales: Mahrt, Niels, Tietze, Alexandra, Künzel, Sven, Franzenburg, Sören, Barbosa, Camilo, Jansen, Gunther, Schulenburg, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390372/
https://www.ncbi.nlm.nih.gov/pubmed/34312522
http://dx.doi.org/10.1038/s41559-021-01511-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390372/
https://www.ncbi.nlm.nih.gov/pubmed/34312522
http://dx.doi.org/10.1038/s41559-021-01511-2

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