A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures

Periodic fever is a characteristic clinical feature of human malaria, but how parasites survive febrile episodes is not known. Although Plasmodium spp. genomes encode a full set of chaperones, they lack the conserved eukaryotic transcription factor HSF1, which activates the expression of chaperones...

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Detalles Bibliográficos
Autores principales: Tintó-Font, Elisabet, Michel-Todó, Lucas, Russell, Timothy J., Casas-Vila, Núria, Conway, David J., Bozdech, Zbynek, Llinás, Manuel, Cortés, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390444/
https://www.ncbi.nlm.nih.gov/pubmed/34400833
http://dx.doi.org/10.1038/s41564-021-00940-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390444/
https://www.ncbi.nlm.nih.gov/pubmed/34400833
http://dx.doi.org/10.1038/s41564-021-00940-w

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