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Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice

Nucleoside-modified, lipid nanoparticle-encapsulated mRNAs have recently emerged as suitable vaccines for influenza viruses and other pathogens in part because the platform allows delivery of multiple antigens in a single immunization. mRNA vaccines allow for easy antigen modification, enabling rapi...

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Detalles Bibliográficos
Autores principales: Freyn, Alec W., Pine, Matthew, Rosado, Victoria C., Benz, Marcel, Muramatsu, Hiromi, Beattie, Mitchell, Tam, Ying K., Krammer, Florian, Palese, Peter, Nachbagauer, Raffael, McMahon, Meagan, Pardi, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390451/
https://www.ncbi.nlm.nih.gov/pubmed/34485597
http://dx.doi.org/10.1016/j.omtm.2021.06.003