Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Although adeno-associated viral (AAV) vector-mediated retinal gene therapies have demonstrated efficacy, the mechanisms underlying dose-dependent retinal inflammation remain poorly understood. Here, we present a quantitative analysis of cellular immune response to subretinal AAV gene therapy in mice...

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Detalles Bibliográficos
Autores principales: Chandler, Laurel C., McClements, Michelle E., Yusuf, Imran H., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E., Xue, Kanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390455/
https://www.ncbi.nlm.nih.gov/pubmed/34485594
http://dx.doi.org/10.1016/j.omtm.2021.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390455/
https://www.ncbi.nlm.nih.gov/pubmed/34485594
http://dx.doi.org/10.1016/j.omtm.2021.05.011

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