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Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Although adeno-associated viral (AAV) vector-mediated retinal gene therapies have demonstrated efficacy, the mechanisms underlying dose-dependent retinal inflammation remain poorly understood. Here, we present a quantitative analysis of cellular immune response to subretinal AAV gene therapy in mice...

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Detalles Bibliográficos
Autores principales:	Chandler, Laurel C., McClements, Michelle E., Yusuf, Imran H., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E., Xue, Kanmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390455/ https://www.ncbi.nlm.nih.gov/pubmed/34485594 http://dx.doi.org/10.1016/j.omtm.2021.05.011

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