Comprehensive polar metabolomics and lipidomics profiling discriminates the transformed from the non-transformed state in colon tissue and cell lines

Colorectal cancer (CRC) is the fourth most lethal disease worldwide. Despite an urgent need for therapeutic advance, selective target identification in a preclinical phase is hampered by molecular and metabolic variations between cellular models. To foster optimal model selection from a translationa...

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Detalles Bibliográficos
Autores principales: Rombouts, Caroline, De Spiegeleer, Margot, Van Meulebroek, Lieven, Vanhaecke, Lynn, De Vos, Winnok H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390467/
https://www.ncbi.nlm.nih.gov/pubmed/34446738
http://dx.doi.org/10.1038/s41598-021-96252-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390467/
https://www.ncbi.nlm.nih.gov/pubmed/34446738
http://dx.doi.org/10.1038/s41598-021-96252-4

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