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Comprehensive polar metabolomics and lipidomics profiling discriminates the transformed from the non-transformed state in colon tissue and cell lines
Colorectal cancer (CRC) is the fourth most lethal disease worldwide. Despite an urgent need for therapeutic advance, selective target identification in a preclinical phase is hampered by molecular and metabolic variations between cellular models. To foster optimal model selection from a translationa...
Autores principales: | Rombouts, Caroline, De Spiegeleer, Margot, Van Meulebroek, Lieven, Vanhaecke, Lynn, De Vos, Winnok H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390467/ https://www.ncbi.nlm.nih.gov/pubmed/34446738 http://dx.doi.org/10.1038/s41598-021-96252-4 |
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