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Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeutics

Developing robust methodology for the sustainable production of red blood cells in vitro is essential for providing an alternative source of clinical-quality blood, particularly for individuals with rare blood group phenotypes. Immortalized erythroid progenitor cell lines are the most promising emer...

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Detalles Bibliográficos
Autores principales: Daniels, Deborah E., Ferguson, Daniel C.J., Griffiths, Rebecca E., Trakarnsanga, Kongtana, Cogan, Nicola, MacInnes, Katherine A., Mordue, Kathryn E., Andrienko, Tatyana, Ferrer-Vicens, Ivan, Ramos Jiménez, Daniel, Lewis, Phillip A., Wilson, Marieangela C., Canham, Maurice A., Kurita, Ryo, Nakamura, Yukio, Anstee, David J., Frayne, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390520/
https://www.ncbi.nlm.nih.gov/pubmed/34485592
http://dx.doi.org/10.1016/j.omtm.2021.06.002