Myeloperoxidase-induced modification of HDL by isolevuglandins inhibits paraoxonase-1 activity

Reduced activity of paraoxonase 1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, has been implicated in the development of atherosclerosis. Post-translational modifications of PON1 may represent important mechanisms leading to reduced PON1 activity. Under atherosclerotic conditions, mye...

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Detalles Bibliográficos
Autores principales: Aggarwal, Geetika, May-Zhang, Linda S., Yermalitsky, Valery, Dikalov, Sergey, Voynov, Maxim A., Amarnath, Venkataraman, Kon, Valentina, Linton, MacRae F., Vickers, Kasey C., Davies, Sean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390528/
https://www.ncbi.nlm.nih.gov/pubmed/34331945
http://dx.doi.org/10.1016/j.jbc.2021.101019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390528/
https://www.ncbi.nlm.nih.gov/pubmed/34331945
http://dx.doi.org/10.1016/j.jbc.2021.101019

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