Cargando…

Myeloperoxidase-induced modification of HDL by isolevuglandins inhibits paraoxonase-1 activity

Reduced activity of paraoxonase 1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, has been implicated in the development of atherosclerosis. Post-translational modifications of PON1 may represent important mechanisms leading to reduced PON1 activity. Under atherosclerotic conditions, mye...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aggarwal, Geetika, May-Zhang, Linda S., Yermalitsky, Valery, Dikalov, Sergey, Voynov, Maxim A., Amarnath, Venkataraman, Kon, Valentina, Linton, MacRae F., Vickers, Kasey C., Davies, Sean S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390528/ https://www.ncbi.nlm.nih.gov/pubmed/34331945 http://dx.doi.org/10.1016/j.jbc.2021.101019

Ejemplares similares

Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation
por: Mayorov, Vladimir, et al.
Publicado: (2019)

Evaluation of Dysfunctional HDL by Myeloperoxidase/Paraoxonase Ratio in Unexplained Infertility Patients Undergoing IVF/ICSI
por: Erdoğan, Kadriye, et al.
Publicado: (2023)

Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus
por: Patrick, David M., et al.
Publicado: (2022)

Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus
por: Patrick, David M., et al.
Publicado: (2022)

Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension
por: Prinsen, Joseph K., et al.
Publicado: (2020)

Scavenging dicarbonyls with 5′-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance
por: Huang, Jiansheng, et al.
Publicado: (2022)

Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion
por: Sedgeman, Leslie R., et al.
Publicado: (2019)

Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
por: Mont, Stacey, et al.
Publicado: (2016)

High-Density Lipoproteins in Kidney Disease
por: Kon, Valentina, et al.
Publicado: (2021)

Increased isolevuglandin-modified proteins in glaucomatous astrocytes
por: Govindarajan, Bharathi, et al.
Publicado: (2009)

Generation and Detection of Levuglandins and Isolevuglandins In Vitro and In Vivo
por: Zhang, Ming, et al.
Publicado: (2011)

Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity
por: Huang, Jiansheng, et al.
Publicado: (2020)

Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr(−/−) mice
por: Tao, Huan, et al.
Publicado: (2020)

Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury
por: Zhong, Jianyong, et al.
Publicado: (2022)

Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation
por: Ruggeri Barbaro, Natalia, et al.
Publicado: (2020)

Paraoxonase-1 and Other HDL Accessory Proteins in Neurological Diseases
por: Marsillach, Judit, et al.
Publicado: (2021)

Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease
por: Wang, Guisong, et al.
Publicado: (2018)

Human Paraoxonase 1 as a Pharmacologic Agent: Limitations and Perspectives
por: Bajaj, Priyanka, et al.
Publicado: (2014)

Understanding Myeloperoxidase-Induced Damage to HDL Structure and Function in the Vessel Wall: Implications for HDL-Based Therapies
por: Marsche, Gunther, et al.
Publicado: (2022)

Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL
por: Schilcher, Irene, et al.
Publicado: (2021)

Associations between myeloperoxidase and paraoxonase-1 and type 2 diabetes in patients with ischemic heart disease
por: Nessler, Katarzyna, et al.
Publicado: (2022)

Isolevuglandins Scavenger Ameliorates Myocardial Ischemic Injury by Suppressing Oxidative Stress, Apoptosis, and Inflammation
por: Guo, Junjie, et al.
Publicado: (2022)

HDL Dysfunctionality (Paraoxonase) Is Worse in Nondiabetic, Postmenopausal African American Than in White Women
por: Gaillard, Trudy, et al.
Publicado: (2011)

HDL-Associated Paraoxonase 1 as a Bridge between Postmenopausal Osteoporosis and Cardiovascular Disease
por: Eren, Esin, et al.
Publicado: (2014)

Paraoxonase 1, HDL Subclasses and Post Surgery Acute Inflammation: A Pilot Study
por: Bains, Yasmin, et al.
Publicado: (2019)

The Adductomics of Isolevuglandins: Oxidation of IsoLG Pyrrole Intermediates Generates Pyrrole–Pyrrole Crosslinks and Lactams
por: Bi, Wenzhao, et al.
Publicado: (2019)

Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport
por: Ikhlef, Souade, et al.
Publicado: (2017)

The Effects of Anthocyanins and Their Microbial Metabolites on the Expression and Enzyme Activities of Paraoxonase 1, an Important Marker of HDL Function
por: Aboufarrag, Hassan T., et al.
Publicado: (2019)

HDL Subclasses and the Distribution of Paraoxonase-1 Activity in Patients with ST-Segment Elevation Acute Myocardial Infarction
por: Djekic, Saska, et al.
Publicado: (2023)

Therapeutic Lifestyle Changes Improve HDL Function by Inhibiting Myeloperoxidase-Mediated Oxidation in Patients With Metabolic Syndrome
por: Mathew, Anna V., et al.
Publicado: (2018)

Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192
por: Aggarwal, Geetika, et al.
Publicado: (2016)

Arylesterase activity of paraoxonase 1 (PON1) on HDL(3) and HDL(2): Relationship with Q192R, C-108T, and L55M polymorphisms
por: Valencia C, Sandra Y., et al.
Publicado: (2021)

Altered inflammation, paraoxonase-1 activity and HDL physicochemical properties in obese humans with and without Prader-Willi syndrome
por: Ferretti, Gianna, et al.
Publicado: (2012)

Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
por: Babaev, Vladimir R., et al.
Publicado: (2014)

Effects of selenium supplementation on paraoxonase-1 and myeloperoxidase activity in subjects with cardiovascular disease: the Selenegene study, a double-blind randomized controlled trial
por: Mirmohammadsadeghi, Amirhossein, et al.
Publicado: (2018)

The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
por: Ebtehaj, Sanam, et al.
Publicado: (2017)

Combined Effects of Curcumin and Lycopene or Bixin in Yoghurt on Inhibition of LDL Oxidation and Increases in HDL and Paraoxonase Levels in Streptozotocin-Diabetic Rats
por: Assis, Renata Pires, et al.
Publicado: (2017)

Paraoxonase/MCS.
por: Rowat, S C
Publicado: (1999)

Introduction to Paraoxonases
por: Aviram, Michael
Publicado: (2012)

Arylesterase Activity of HDL Associated Paraoxonase as a Potential Prognostic Marker in Patients With Sepsis and Septic Shock—A Prospective Pilot Study
por: Reisinger, Alexander C., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4a5fnl84flait97cpccgogrhpm