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The DNA-binding protein CST associates with the cohesin complex and promotes chromosome cohesion

Sister chromatid cohesion (SCC), the pairing of sister chromatids after DNA replication until mitosis, is established by loading of the cohesin complex on newly replicated chromatids. Cohesin must then be maintained until mitosis to prevent segregation defects and aneuploidy. However, how SCC is est...

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Detalles Bibliográficos
Autores principales: Schuck, P. Logan, Ball, Lauren E., Stewart, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390553/
https://www.ncbi.nlm.nih.gov/pubmed/34339741
http://dx.doi.org/10.1016/j.jbc.2021.101026