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Non-toxic polymer nanovectors for improved delivery of dexamethasone

Dexamethasone (Dex) is a highly insoluble front-line drug used in cancer therapy. Data from clinical trials indicates that the pharmacokinetics of Dex vary considerably between patients and prolonging drug exposure rather than increasing absolute dose may improve efficacy. Non-toxic, fully biodegrad...

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Detalles Bibliográficos
Autores principales: Ede, Benjamin C., Diamanti, Paraskevi, Williams, David S., Blair, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390661/
https://www.ncbi.nlm.nih.gov/pubmed/34446801
http://dx.doi.org/10.1038/s41598-021-96797-4