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A novel neurotensin/xenin fusion peptide enhances β-cell function and exhibits antidiabetic efficacy in high-fat fed mice

Neurotensin and xenin possess antidiabetic potential, mediated in part through augmentation of incretin hormone, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), action. In the present study, fragment peptides of neurotensin and xenin, acetyl-neurotensin and xe...

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Detalles Bibliográficos
Autores principales: Perry, Rachele A., Craig, Sarah. L., Gault, Victor A., Flatt, Peter R., Irwin, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390788/
https://www.ncbi.nlm.nih.gov/pubmed/34370015
http://dx.doi.org/10.1042/BSR20211275