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Stochastic reaction-diffusion modeling of calcium dynamics in 3D dendritic spines of Purkinje cells

Calcium (Ca(2+)) is a second messenger assumed to control changes in synaptic strength in the form of both long-term depression and long-term potentiation at Purkinje cell dendritic spine synapses via inositol trisphosphate (IP(3))-induced Ca(2+) release. These Ca(2+) transients happen in response t...

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Detalles Bibliográficos
Autores principales: Friedhoff, Victor Nicolai, Antunes, Gabriela, Falcke, Martin, Simões de Souza, Fabio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390834/
https://www.ncbi.nlm.nih.gov/pubmed/33887224
http://dx.doi.org/10.1016/j.bpj.2021.03.027