Cargando…

Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance

Infectious diseases continually pose global medical challenges. The transcription factor GATA2 establishes gene networks and defines cellular identity in hematopoietic stem/progenitor cells and in progeny committed to specific lineages. GATA2-haploinsufficient patients exhibit a spectrum of immunode...

Descripción completa

Detalles Bibliográficos
Autores principales: Takai, Jun, Shimada, Takashi, Nakamura, Tadaho, Engel, James Douglas, Moriguchi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390858/
https://www.ncbi.nlm.nih.gov/pubmed/34471858
http://dx.doi.org/10.1016/j.isci.2021.102836