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Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance
Infectious diseases continually pose global medical challenges. The transcription factor GATA2 establishes gene networks and defines cellular identity in hematopoietic stem/progenitor cells and in progeny committed to specific lineages. GATA2-haploinsufficient patients exhibit a spectrum of immunode...
Autores principales: | Takai, Jun, Shimada, Takashi, Nakamura, Tadaho, Engel, James Douglas, Moriguchi, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390858/ https://www.ncbi.nlm.nih.gov/pubmed/34471858 http://dx.doi.org/10.1016/j.isci.2021.102836 |
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