Two alternative conformations of mRNA in the human ribosome during elongation and termination of translation as revealed by EPR spectroscopy

The conformation of mRNA in the region of the human 80S ribosome decoding site was monitored using 11-mer mRNA analogues that bore nitroxide spin labels attached to the terminal nucleotide bases. Intramolecular spin–spin distances were measured by DEER/PELDOR spectroscopy in model complexes mimickin...

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Detalles Bibliográficos
Autores principales: Bulygin, Konstantin N., Timofeev, Ivan O., Malygin, Alexey A., Graifer, Dmitri M., Meschaninova, Maria I., Venyaminova, Alya G., Krumkacheva, Olesya A., Fedin, Matvey V., Yu. Frolova, Ludmila, Karpova, Galina G., Bagryanskaya, Elena G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390954/
https://www.ncbi.nlm.nih.gov/pubmed/34504663
http://dx.doi.org/10.1016/j.csbj.2021.08.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390954/
https://www.ncbi.nlm.nih.gov/pubmed/34504663
http://dx.doi.org/10.1016/j.csbj.2021.08.024

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