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CCNE1 amplification among metastatic sites in patients with gynecologic high-grade serous carcinoma

OBJECTIVE: We sought to characterize the variability of CCNE1 amplification among metastatic sites of CCNE1 amplified high grade serous carcinoma (HGSC) cases to investigate the feasibility of targeting this alteration for therapeutic purposes. METHODS: Patients with CCNE1 amplified HGSC who underwe...

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Detalles Bibliográficos
Autores principales: Margolis, Benjamin, Dao, Fanny, Licciardi, Michael, Misirlioglu, Selim, Olvera, Narciso, Ramaswami, Sitharam, Levine, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391017/
https://www.ncbi.nlm.nih.gov/pubmed/34485660
http://dx.doi.org/10.1016/j.gore.2021.100850