Cargando…

Spatially resolved free-energy contributions of native fold and molten-globule-like Crambin

The folding stability of a protein is governed by the free-energy difference between its folded and unfolded states, which results from a delicate balance of much larger but almost compensating enthalpic and entropic contributions. The balance can therefore easily be shifted by an external disturban...

Descripción completa

Detalles Bibliográficos
Autores principales: Heinz, Leonard P., Grubmüller, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391029/
https://www.ncbi.nlm.nih.gov/pubmed/34087209
http://dx.doi.org/10.1016/j.bpj.2021.05.019