Scavenging amyloid oligomers from neurons with silica nanobowls: Implications for amyloid diseases

Amyloid-β (Aβ) oligomers are toxic species implicated in Alzheimer’s disease (AD). The prevailing hypothesis implicates a major role of membrane-associated amyloid oligomers in AD pathology. Our silica nanobowls (NB) coated with lipid-polymer have submicromolar affinity for Aβ binding. We demonstrat...

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Detalles Bibliográficos
Autores principales: Sant, Vrinda, Som, Madhura, Karkisaval, Abhijith G., Carnahan, Parker, Lal, Ratnesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391079/
https://www.ncbi.nlm.nih.gov/pubmed/34242592
http://dx.doi.org/10.1016/j.bpj.2021.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391079/
https://www.ncbi.nlm.nih.gov/pubmed/34242592
http://dx.doi.org/10.1016/j.bpj.2021.07.002

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