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Scavenging amyloid oligomers from neurons with silica nanobowls: Implications for amyloid diseases
Amyloid-β (Aβ) oligomers are toxic species implicated in Alzheimer’s disease (AD). The prevailing hypothesis implicates a major role of membrane-associated amyloid oligomers in AD pathology. Our silica nanobowls (NB) coated with lipid-polymer have submicromolar affinity for Aβ binding. We demonstrat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391079/ https://www.ncbi.nlm.nih.gov/pubmed/34242592 http://dx.doi.org/10.1016/j.bpj.2021.07.002 |