Macromolecular crowding modulates α-synuclein amyloid fiber growth

The crowdedness of living cells, hundreds of milligrams per milliliter of macromolecules, may affect protein folding, function, and misfolding. Still, such processes are most often studied in dilute solutions in vitro. To assess consequences of the in vivo milieu, we here investigated the effects of...

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Detalles Bibliográficos
Autores principales: Horvath, Istvan, Kumar, Ranjeet, Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391083/
https://www.ncbi.nlm.nih.gov/pubmed/34242594
http://dx.doi.org/10.1016/j.bpj.2021.06.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391083/
https://www.ncbi.nlm.nih.gov/pubmed/34242594
http://dx.doi.org/10.1016/j.bpj.2021.06.032

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