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Macromolecular crowding modulates α-synuclein amyloid fiber growth
The crowdedness of living cells, hundreds of milligrams per milliliter of macromolecules, may affect protein folding, function, and misfolding. Still, such processes are most often studied in dilute solutions in vitro. To assess consequences of the in vivo milieu, we here investigated the effects of...
Autores principales: | Horvath, Istvan, Kumar, Ranjeet, Wittung-Stafshede, Pernilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391083/ https://www.ncbi.nlm.nih.gov/pubmed/34242594 http://dx.doi.org/10.1016/j.bpj.2021.06.032 |
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