Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1

During metaphase, in response to improper kinetochore‐microtubule attachments, the spindle assembly checkpoint (SAC) activates the mitotic checkpoint complex (MCC), an inhibitor of the anaphase‐promoting complex/cyclosome (APC/C). This process is orchestrated by the kinase Mps1, which initiates the...

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Detalles Bibliográficos
Autores principales: Fischer, Elyse S, Yu, Conny W H, Bellini, Dom, McLaughlin, Stephen H, Orr, Christian M, Wagner, Armin, Freund, Stefan M V, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391104/
https://www.ncbi.nlm.nih.gov/pubmed/34013668
http://dx.doi.org/10.15252/embr.202052242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391104/
https://www.ncbi.nlm.nih.gov/pubmed/34013668
http://dx.doi.org/10.15252/embr.202052242

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