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LightSpot(®)-FL-1 Fluorescent Probe: An Innovative Tool for Cancer Drug Resistance Analysis by Direct Detection and Quantification of the P-glycoprotein (P-gp) on Monolayer Culture and Spheroid Triple Negative Breast Cancer Models

SIMPLE SUMMARY: Tumoral drug resistance is mainly caused by multidrug resistance transporters (MDR), such as the P-gp, which presents high clinical interest. For this reason, the P-gp-mediated drug resistance diagnosis may be very relevant for optimizing anticancer treatment efficacy. However, the l...

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Detalles Bibliográficos
Autores principales: Goisnard, Antoine, Daumar, Pierre, Dubois, Clémence, Aubel, Corinne, Roux, Manon, Depresle, Marie, Gauthier, Jean, Vidalinc, Bernard, Penault-Llorca, Frédérique, Mounetou, Emmanuelle, Bamdad, Mahchid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391116/
https://www.ncbi.nlm.nih.gov/pubmed/34439204
http://dx.doi.org/10.3390/cancers13164050