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Hitting the Bull’s-Eye: Mesothelin’s Role as a Biomarker and Therapeutic Target for Malignant Pleural Mesothelioma

SIMPLE SUMMARY: Mesothelioma is a deadly disease with a dismal prognosis. Since its discovery, mesothelin, a cell surface protein, has been a promising biomarker and therapeutic target due to its overexpression in mesothelioma and limited expression in normal cells. This review summarizes the clinic...

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Detalles Bibliográficos
Autores principales: Yeo, Dannel, Castelletti, Laura, van Zandwijk, Nico, Rasko, John E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391149/
https://www.ncbi.nlm.nih.gov/pubmed/34439085
http://dx.doi.org/10.3390/cancers13163932