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Evaluation of Micro Satellite Instability and Mismatch Repair Status in Different Solid Tumors: A Multicenter Analysis in a Real World Setting

Immune-checkpoint inhibitors (ICIs) play a key role in the treatment of advanced stage colorectal cancer (CRC) patients featuring a deficient DNA mismatch repair (dMMR) system or a high microsatellite instability (MSI-H) profile. However, beyond the established role in CRC patients, ICIs have highly...

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Detalles Bibliográficos
Autores principales: Malapelle, Umberto, Parente, Paola, Pepe, Francesco, De Luca, Caterina, Pisapia, Pasquale, Sgariglia, Roberta, Nacchio, Mariantonia, Gragnano, Gianluca, Russo, Gianluca, Conticelli, Floriana, Bellevicine, Claudio, Vigliar, Elena, Iaccarino, Antonino, Covelli, Claudia, Balistreri, Mariangela, Clemente, Celeste, Perrone, Giovanni, Danza, Angela, Scaramuzzi, Fabio, Fassan, Matteo, Troncone, Giancarlo, Graziano, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391221/
https://www.ncbi.nlm.nih.gov/pubmed/34440647
http://dx.doi.org/10.3390/cells10081878