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Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment

SIMPLE SUMMARY: Metastatic brain melanoma is a common metastatic cancer with a high mortality rate. Current clinical regimens use the anti-angiogenesis drug bevacizumab (Avastin) and/or Lipo-DOX, a drug capable penetrating the blood–brain barrier; however, both commonly result in adverse side effect...

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Detalles Bibliográficos
Autores principales: Yang, Chung-Chih, Chang, Meng-Ting, Chang, Cheng-Kuei, Shyur, Lie-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391228/
https://www.ncbi.nlm.nih.gov/pubmed/34439274
http://dx.doi.org/10.3390/cancers13164120