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BTK, NUTM2A, and PRPF19 Are Novel KMT2A Partner Genes in Childhood Acute Leukemia

Chromosomal rearrangements of the human KMT2A/MLL gene are associated with acute leukemias, especially in infants. KMT2A is rearranged with a big variety of partner genes and in multiple breakpoint locations. Detection of all types of KMT2A rearrangements is an essential part of acute leukemia initi...

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Detalles Bibliográficos
Autores principales: Zerkalenkova, Elena, Lebedeva, Svetlana, Borkovskaia, Aleksandra, Soldatkina, Olga, Plekhanova, Olga, Tsaur, Grigory, Maschan, Michael, Maschan, Aleksey, Novichkova, Galina, Olshanskaya, Yulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391293/
https://www.ncbi.nlm.nih.gov/pubmed/34440129
http://dx.doi.org/10.3390/biomedicines9080924