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L-myc Gene Expression in Canine Fetal Fibroblasts Promotes Self-Renewal Capacity but Not Tumor Formation

Canines are useful in mammalian preclinical studies because they are larger than rodents and share many diseases with humans. Canine fetal fibroblast cells (CFFs) are an easily accessible source of somatic cells. However, they are easily driven to senescence and become unusable with continuous in vi...

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Detalles Bibliográficos
Autores principales: Kim, So Hee, Kim, Bokyung, Kim, Jung Hak, Kim, Dong-Hoon, Lee, Seung Hoon, Lee, Dong-Seok, Lee, Hong J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391401/
https://www.ncbi.nlm.nih.gov/pubmed/34440750
http://dx.doi.org/10.3390/cells10081980