Nitric Oxide Synthase Dependency in Hydroxyurea Inhibition of Erythroid Progenitor Growth

Hydroxyurea (HU) causes nitric oxide (NO) bioactivation, acting as both a NO donor and a stimulator of NO synthase (NOS). To examine whether HU effects are NO mediated by chemical degradation or enzymatic induction, we studied human and mouse erythroid cells during proliferation, apoptosis, and diff...

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Detalles Bibliográficos
Autores principales: Subotički, Tijana, Ajtić, Olivera Mitrović, Đikić, Dragoslava, Santibanez, Juan F., Tošić, Milica, Čokić, Vladan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391407/
https://www.ncbi.nlm.nih.gov/pubmed/34440315
http://dx.doi.org/10.3390/genes12081145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391407/
https://www.ncbi.nlm.nih.gov/pubmed/34440315
http://dx.doi.org/10.3390/genes12081145

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