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Novel Insights into the Molecular Regulation of Ribonucleotide Reductase in Adrenocortical Carcinoma Treatment

SIMPLE SUMMARY: The current clinical gold standard etoposide, doxorubicin, cisplatin, and mitotane (EDP-M) is not satisfying for the treatment of adrenocortical carcinoma (ACC). However, clinical translation of novel, preclinically promising therapies were unfortunately disappointing in recent years...

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Detalles Bibliográficos
Autores principales: Bothou, Christina, Sharma, Ashish, Oo, Adrian, Kim, Baek, Perge, Pal, Igaz, Peter, Ronchi, Cristina L., Shapiro, Igor, Hantel, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391410/
https://www.ncbi.nlm.nih.gov/pubmed/34439352
http://dx.doi.org/10.3390/cancers13164200