The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells

Pancreatic stellate cells (PSCs) are important pancreatic fibrogenic cells that interact with pancreatic cancer cells to promote the progression of pancreatic ductal adenocarcinoma (PDAC). In the tumor microenvironment (TME), several factors such as cytokines and nucleotides contribute to this inter...

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Detalles Bibliográficos
Autores principales: Magni, Lara, Bouazzi, Rayhana, Heredero Olmedilla, Hugo, Petersen, Patricia S. S., Tozzi, Marco, Novak, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391419/
https://www.ncbi.nlm.nih.gov/pubmed/34440697
http://dx.doi.org/10.3390/cells10081928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391419/
https://www.ncbi.nlm.nih.gov/pubmed/34440697
http://dx.doi.org/10.3390/cells10081928

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