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The P2X7 Receptor Stimulates IL-6 Release from Pancreatic Stellate Cells and Tocilizumab Prevents Activation of STAT3 in Pancreatic Cancer Cells
Pancreatic stellate cells (PSCs) are important pancreatic fibrogenic cells that interact with pancreatic cancer cells to promote the progression of pancreatic ductal adenocarcinoma (PDAC). In the tumor microenvironment (TME), several factors such as cytokines and nucleotides contribute to this inter...
Autores principales: | Magni, Lara, Bouazzi, Rayhana, Heredero Olmedilla, Hugo, Petersen, Patricia S. S., Tozzi, Marco, Novak, Ivana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391419/ https://www.ncbi.nlm.nih.gov/pubmed/34440697 http://dx.doi.org/10.3390/cells10081928 |
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