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Kinins and Their Receptors as Potential Therapeutic Targets in Retinal Pathologies

The kallikrein-kinin system (KKS) contributes to retinal inflammation and neovascularization, notably in diabetic retinopathy (DR) and neovascular age-related macular degeneration (AMD). Bradykinin type 1 (B1R) and type 2 (B2R) receptors are G-protein-coupled receptors that sense and mediate the eff...

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Detalles Bibliográficos
Autores principales: Othman, Rahmeh, Cagnone, Gael, Joyal, Jean-Sébastien, Vaucher, Elvire, Couture, Réjean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391508/
https://www.ncbi.nlm.nih.gov/pubmed/34440682
http://dx.doi.org/10.3390/cells10081913