Cargando…
Kinins and Their Receptors as Potential Therapeutic Targets in Retinal Pathologies
The kallikrein-kinin system (KKS) contributes to retinal inflammation and neovascularization, notably in diabetic retinopathy (DR) and neovascular age-related macular degeneration (AMD). Bradykinin type 1 (B1R) and type 2 (B2R) receptors are G-protein-coupled receptors that sense and mediate the eff...
Autores principales: | Othman, Rahmeh, Cagnone, Gael, Joyal, Jean-Sébastien, Vaucher, Elvire, Couture, Réjean |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391508/ https://www.ncbi.nlm.nih.gov/pubmed/34440682 http://dx.doi.org/10.3390/cells10081913 |
Ejemplares similares
-
Differential Expression of Kinin Receptors in Human Wet and Dry Age-Related Macular Degeneration Retinae
por: Othman, Rahmeh, et al.
Publicado: (2020) -
Bradykinin Type 1 Receptor – Inducible Nitric Oxide Synthase: A New Axis Implicated in Diabetic Retinopathy
por: Othman, Rahmeh, et al.
Publicado: (2019) -
Ocular Application of the Kinin B(1) Receptor Antagonist LF22-0542 Inhibits Retinal Inflammation and Oxidative Stress in Streptozotocin-Diabetic Rats
por: Pouliot, Mylène, et al.
Publicado: (2012) -
Reciprocal Regulatory Interaction between TRPV1 and Kinin B1 Receptor in a Rat Neuropathic Pain Model
por: Cernit, Veronica, et al.
Publicado: (2020) -
Prevention of Inflammation, Neovascularization, and Retinal Dysfunction by Kinin B(1) Receptor Antagonism in a Mouse Model of Age-Related Macular Degeneration
por: Bhat, Menakshi, et al.
Publicado: (2023)