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Thrombospondin-1 Silencing Improves Lymphocyte Infiltration in Tumors and Response to Anti-PD-1 in Triple-Negative Breast Cancer

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) is associated with a poor prognosis, and the development of better therapeutic strategies is required. Herein, we investigated the role of the anti-angiogenic thrombospondin-1 (TSP1) in TNBC. TSP1 expression in tumor biopsies from TNBC patients wa...

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Detalles Bibliográficos
Autores principales: Marcheteau, Elie, Farge, Thomas, Pérès, Michaël, Labrousse, Guillaume, Tenet, Julie, Delmas, Stéphanie, Chusseau, Maud, Duprez-Paumier, Raphaëlle, Franchet, Camille, Dalenc, Florence, Imbert, Caroline, Noujarède, Justine, Colacios, Céline, Prats, Hervé, Cabon, Florence, Ségui, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391594/
https://www.ncbi.nlm.nih.gov/pubmed/34439212
http://dx.doi.org/10.3390/cancers13164059