The Function of the Mutant p53-R175H in Cancer

SIMPLE SUMMARY: TP53 is one of the most well-known and intensively studied tumor-suppressor genes. TP53 is also the most commonly mutated gene in cancer. Many TP53 mutations are missense mutations and are located in several hotspots. Increasing evidence has shown that these hotspot mutations both lo...

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Detalles Bibliográficos
Autores principales: Chiang, Yen-Ting, Chien, Yi-Chung, Lin, Yu-Heng, Wu, Hui-Hsuan, Lee, Dung-Fang, Yu, Yung-Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391618/
https://www.ncbi.nlm.nih.gov/pubmed/34439241
http://dx.doi.org/10.3390/cancers13164088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391618/
https://www.ncbi.nlm.nih.gov/pubmed/34439241
http://dx.doi.org/10.3390/cancers13164088

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