β-Adrenergic Stimulation Synchronizes a Broad Spectrum of Action Potential Firing Rates of Cardiac Pacemaker Cells toward a Higher Population Average

The heartbeat is initiated by pacemaker cells residing in the sinoatrial node (SAN). SAN cells generate spontaneous action potentials (APs), i.e., normal automaticity. The sympathetic nervous system increases the heart rate commensurate with the cardiac output demand via stimulation of SAN β-adrener...

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Detalles Bibliográficos
Autores principales: Kim, Mary S., Monfredi, Oliver, Maltseva, Larissa A., Lakatta, Edward G., Maltsev, Victor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391682/
https://www.ncbi.nlm.nih.gov/pubmed/34440893
http://dx.doi.org/10.3390/cells10082124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391682/
https://www.ncbi.nlm.nih.gov/pubmed/34440893
http://dx.doi.org/10.3390/cells10082124

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