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Integration of Molecular Information in Risk Assessment of Patients with Myeloproliferative Neoplasms

Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) are clonal disorders of a hematopoietic stem cell, characterized by an abnormal proliferation of largely mature cells driven by mutations in JAK2, CALR, and MPL. All these mutations lead to a constitutive activation of the JAK-STAT...

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Detalles Bibliográficos
Autores principales: Loscocco, Giuseppe G., Coltro, Giacomo, Guglielmelli, Paola, Vannucchi, Alessandro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391705/
https://www.ncbi.nlm.nih.gov/pubmed/34440731
http://dx.doi.org/10.3390/cells10081962