Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphodynamics

Nonmuscle myosin II (NM II) is an integral part of essential cellular processes, including adhesion and migration. Mammalian cells express up to three isoforms termed NM IIA, B, and C. We used U2OS cells to create CRISPR/Cas9-based knockouts of all three isoforms and analyzed the phenotypes on homog...

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Detalles Bibliográficos
Autores principales: Weißenbruch, Kai, Grewe, Justin, Hippler, Marc, Fladung, Magdalena, Tremmel, Moritz, Stricker, Kathrin, Schwarz, Ulrich Sebastian, Bastmeyer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391736/
https://www.ncbi.nlm.nih.gov/pubmed/34374341
http://dx.doi.org/10.7554/eLife.71888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391736/
https://www.ncbi.nlm.nih.gov/pubmed/34374341
http://dx.doi.org/10.7554/eLife.71888

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