Empirical comparison of genotoxic potency estimations: the in vitro DNA-damage ToxTracker endpoints versus the in vivo micronucleus assay

Genetic toxicology is an essential component of compound safety assessment. In the face of a barrage of new compounds, higher throughput, less ethically divisive in vitro approaches capable of effective, human-relevant hazard identification and prioritisation are increasingly important. One such app...

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Detalles Bibliográficos
Autores principales: Wills, John W, Halkes-Wellstead, Elias, Summers, Huw D, Rees, Paul, Johnson, George E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Manuscripts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391785/
https://www.ncbi.nlm.nih.gov/pubmed/34111295
http://dx.doi.org/10.1093/mutage/geab020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391785/
https://www.ncbi.nlm.nih.gov/pubmed/34111295
http://dx.doi.org/10.1093/mutage/geab020

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