Enthalpy–Entropy Compensation in the Promiscuous Interaction of an Intrinsically Disordered Protein with Homologous Protein Partners

Intrinsically disordered proteins (IDPs) can engage in promiscuous interactions with their protein targets; however, it is not clear how this feature is encoded in the primary sequence of the IDPs and to what extent the surface properties and the shape of the binding cavity dictate the binding mode...

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Detalles Bibliográficos
Autores principales: Kragelj, Jaka, Orand, Thibault, Delaforge, Elise, Tengo, Laura, Blackledge, Martin, Palencia, Andrés, Jensen, Malene Ringkjøbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391806/
https://www.ncbi.nlm.nih.gov/pubmed/34439869
http://dx.doi.org/10.3390/biom11081204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391806/
https://www.ncbi.nlm.nih.gov/pubmed/34439869
http://dx.doi.org/10.3390/biom11081204

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