Cargando…

Search for a Functional Genetic Variant Mimicking the Effect of SGLT2 Inhibitor Treatment

SGLT2 inhibitors (SGLT2i) block renal glucose reabsorption. Due to the unexpected beneficial observations in type 2 diabetic patients potentially related to increased natriuresis, SGLT2i are also studied for heart failure treatment. This study aimed to identify genetic variants mimicking SGLT2i to f...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Siqi, Said, M. Abdullah, Groot, Hilde E., van der Most, Peter J., Thio, Chris H. L., van de Vegte, Yordi J., Verweij, Niek, Snieder, Harold, van der Harst, Pim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391850/
https://www.ncbi.nlm.nih.gov/pubmed/34440348
http://dx.doi.org/10.3390/genes12081174