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Evidence for Multiple Origins of De Novo Formed Vascular Smooth Muscle Cells in Pulmonary Hypertension: Challenging the Dominant Model of Pre-Existing Smooth Muscle Expansion

Vascular remodeling is a prominent feature of pulmonary hypertension. This process involves increased muscularization of already muscularized vessels as well as neo-muscularization of non-muscularized vessels. The cell-of-origin of the newly formed vascular smooth muscle cells has been a subject of...

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Detalles Bibliográficos
Autores principales: Chu, Xuran, Ahmadvand, Negah, Zhang, Jin-San, Seeger, Werner, Bellusci, Saverio, El Agha, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391896/
https://www.ncbi.nlm.nih.gov/pubmed/34444333
http://dx.doi.org/10.3390/ijerph18168584