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Helicobacter pylori CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation

SIMPLE SUMMARY: Various microbial pathogens target the actin-binding protein cortactin to promote their own uptake, proliferation and spread, and exhibit proposed roles in human cancerogenesis. We aimed to study the molecular mechanisms of how the gastric pathogen Helicobacter pylori hijacks cortact...

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Detalles Bibliográficos
Autores principales: Tegtmeyer, Nicole, Harrer, Aileen, Rottner, Klemens, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391897/
https://www.ncbi.nlm.nih.gov/pubmed/34439396
http://dx.doi.org/10.3390/cancers13164241