The Combined Effect of Branching and Elongation on the Bioactivity Profile of Phytocannabinoids. Part I: Thermo-TRPs

The affinity of cannabinoids for their CB(1) and CB(2) metabotropic receptors is dramatically affected by a combination of α-branching and elongation of their alkyl substituent, a maneuver exemplified by the n-pentyl -> α,α-dimethylheptyl (DMH) swap. The effect of this change on other cannabinoid...

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Detalles Bibliográficos
Autores principales: Mattoteia, Daiana, Schiano Moriello, Aniello, Taglialatela-Scafati, Orazio, Amodeo, Pietro, De Petrocellis, Luciano, Appendino, Giovanni, Vitale, Rosa Maria, Caprioglio, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391922/
https://www.ncbi.nlm.nih.gov/pubmed/34440274
http://dx.doi.org/10.3390/biomedicines9081070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391922/
https://www.ncbi.nlm.nih.gov/pubmed/34440274
http://dx.doi.org/10.3390/biomedicines9081070

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